Reference Armadillo v1.1

NameAncestorCC
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Publication(s)Ancestors 1.0: a web server for ancestral sequence reconstruction. Diallo AB, Makarenkov V, Blanchette M. Bioinformatics. 2010 Jan 1;26(1):130-1. Epub 2009 Oct 22. Exact and heuristic algorithms for the Indel Maximum Likelihood Problem. Diallo AB, Makarenkov V, Blanchette M. J Comput Biol. 2007 May;14(4):446-61.

Websitehttp://ancestors.bioinfo.uqam.ca/ancestorWeb/

DescriptionThe computational inference of ancestral genomes consists of five difficult steps: identifying syntenic regions, inferring ancestral arrangement of syntenic regions, aligning multiple sequences, reconstructing the insertion and deletion history and finally inferring substitutions. Each of these steps have received lot of attention in the past years. However, there currently exists no framework that integrates all of the different steps in an easy workflow. Here, we introduce Ancestors 1.0, a web server allowing one to easily and quickly perform the last three steps of the ancestral genome reconstruction procedure. It implements several alignment algorithms, an indel maximum likelihood solver and a context-dependent maximum likelihood substitution inference algorithm. The results presented by the server include the posterior probabilities for the last two steps of the ancestral genome reconstruction and the expected error rate of each ancestral base prediction. AVAILABILITY: The Ancestors 1.0 is available at http://ancestors.bioinfo.uqam.ca/ancestorWeb/. (C) Abdoulaye Banire Diallo.

Input (2) Alignment
Tree
Output (4) HTML
Results
Alignment
OutputText
Keywords (1) Ancestrale sequence reconstruction  
Related (3) Blast (NCBI)  Comments  Comments  
Sample workflowANCESTORCC.properties.db